February 25, 2011 by admin
A MeReC bulletin has pulled together useful information and guidelines about the management of constipation in children and adults using three case studies. It comments on how the wide variation in normal bowel function can make diagnosis of constipation subjective and on how public perceptions have changed. Because there is not enough clinical evidence to compare the efficacy of some laxatives, prescribers consider cost, symptoms and acceptability to patients.
January 24, 2011 by admin
NICE has recommended prucalopride as an option in certain circumstances for women with chronic constipation: treatment with at least two laxatives from different classes, at the highest tolerated recommended dose for at least six months, must have failed to provide adequate relief; and invasive treatment is being considered.
If prucalopride is not effective after 4 weeks, the woman should be examined again and the treatment reconsidered. Only clinicians with experience in treating chronic constipation should prescribe prucalopride, and they should review previous treatments carefully first.